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Excedrin Migraine Relief Caplets for Migraine Symptoms, Acetaminophen 500mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever, 24 Count
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Purchase options and add-ons
Brand | Excedrin |
Special Feature | fast_acting |
Item Weight | 0.09 Pounds |
Item dimensions L x W x H | 1.73 x 2.97 x 1.68 inches |
Product Benefits | Headache Relief, Pain Relief |
About this item
- One bottle of 24 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
- Migraine medicine that delivers effective migraine headache pain relief
- Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
- Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
- Delivers a powerful triple action formula with two pain fighters and an amplifier
- Migraine relief medicine available in convenient caplet form
- For some, these Excedrin Migraine caplets relieve migraine pain in 30 minutes
- HSA and FSA eligible product
Competitively priced item
Frequently bought together

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From the manufacturer




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Excedrin Migraine
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Excedrin PM
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Customer Reviews |
4.8 out of 5 stars 11,321
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4.8 out of 5 stars 2,462
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4.8 out of 5 stars 7,004
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4.8 out of 5 stars 4,200
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Price | $18.38$18.38 | $11.99$11.99 | $11.48$11.48 | $15.99$15.99 |
Contains Acetaminophen | ✓ | ✓ | ✓ | ✓ |
Contains Aspirin | ✓ | ✓ | no data | ✓ |
Contains Caffeine | ✓ | ✓ | ✓ | no data |
Contains Diphenhydramine Citrate | no data | no data | no data | ✓ |
Dose | 2 caplets per day | 2 caplets every 6 hours, maximum of 8 caplets per day | 2 caplets every 6 hours, maximum of 6 caplets per day | 2 caplets per day |
Age | 18 years and older | 12 years and older | 12 years and older | 12 years and older |
Product Description
Excedrin Migraine Relief Caplets work fast for migraine pain relief, making Excedrin Migraine the #1 neurologist recommended OTC treatment for migraines.(1) Available in convenient caplet form, this powerful migraine medicine delivers a specialized triple action formula containing two pain fighters and an amplifier. These Excedrin caplets combine aspirin and acetaminophen with caffeine to provide migraine relief, including migraine headache pain, sensitivity to light and sound, and nausea. For some, this migraine headache relief medicine starts relieving migraine pain in 30 minutes. (1) Among OTC medicine for migraines IQVIA, Inc., 2018
Product details
- Is Discontinued By Manufacturer : No
- Product Dimensions : 1.73 x 2.97 x 1.68 inches; 1.44 ounces
- Item model number : 300672039248
- Date First Available : October 5, 2012
- Manufacturer : Haleon US Services Inc.
- ASIN : B00AFDL4Z2
- Country of Origin : USA
- Best Sellers Rank: #7,417 in Health & Household (See Top 100 in Health & Household)
- #40 in Acetaminophen
- Customer Reviews:
Compare with similar items
This Item ![]() Excedrin Migraine Relief Caplets for Migraine Symptoms, Acetaminophen 500mg, Aspirin 250mg, Caffeine 65mg, Pain Reliever, 24 Count | Recommendations | |||||
Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | Try again! Added to Cart | |
Price | -29% $4.97$4.97 List: $7.00 | $19.73$19.73 | $15.99$15.99 | -33% $3.99$3.99 List: $5.99 | $4.97$4.97 | -5% $14.80$14.80 Typical: $15.54 |
Price Per Unit | $0.21 / count | $0.10 / count | $0.16 / count | $0.50 / count | $0.21 / count | $0.07 / count |
Delivery | Get it as soon as Sunday, Jun 15 | Get it as soon as Sunday, Jun 15 | Get it as soon as Sunday, Jun 15 | Get it as soon as Sunday, Jun 15 | Get it as soon as Sunday, Jun 15 | Get it as soon as Sunday, Jun 15 |
Customer Ratings | ||||||
Sold By | Amazon.com | Amazon.com | Amazon.com | Amazon.com | Amazon.com | Amazon.com |
active ingredients | (in each caplet) Acetaminophen 250 mg Pain reliever Aspirin 250 mg (NSAID*) - Pain reliever Caffeine 65 mg - Pain reliever aid *nonsteroidal anti-inflammatory drug | (in each caplet) Acetaminophen 250 mg - Pain reliever Aspirin 250 mg (NSAID*) - Pain reliever Caffeine 65 mg - Pain reliever aid *nonsteroidal anti-inflammatory drug | Acetaminophen | ginger | (in each caplet)Acetaminophen 250 mg - Pain relieverAspirin 250 mg (NSAID*) - Pain relieverCaffeine 65 mg - Pain reliever aid*nonsteroidal anti-inflammatory drug | Acetaminophen 250 mg, Aspirin 250 mg (NSAID*), Caffeine 65 mg |
specific uses | Nausea, Migraine, Headache | Cold, Menstrual Pain, Toothache, Muscle Pain | Headache Relief,Pain Relief | Motion Sickness | Arthritis, Muscle Pain, Menstrual Pain, Cold | Migraine |
form | Caplet | Caplet | Caplets | Tablets | Caplet | Tablet |
weight | 0.09 pounds | 5.79 ounces | 0.15 pounds | 0.04 pounds | — | — |
product benefit | Headache Relief, Pain Relief | Headache Relief, Pain Relief | Headache Health | Motion Sickness Relief | Headache Relief | Headache Relief, Pain Relief |
serving suggestion | 2 caplets | — | — | When using this product:Drowsiness may occur, avoid alcoholic drinks.Alcohol, sedatives, and tranquilizers may increase drowsiness. Be careful when driving a motor vehicle or operating machinery | 2 caplets | 2 caplets |
flavor | — | Unflavored | — | Motion Sickness | Unflavored | Unflavored |
dosage form | — | Caplet | — | Tablets | Tablets | — |
Important information
Safety Information
Reye's syndrome: children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness.Allergy alert: aspirin may cause a severe allergic reaction which may include: Hives. Facial swelling. Asthma (wheezing). Shock.Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take:More than 2 caplets in 24 hours, which is the maximum daily amount.With other drugs containing acetaminophen.3 or more alcoholic drinks every day while using this product.Stomach bleeding warning: this product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you:Are age 60 or older.Have had stomach ulcers or bleeding problems.Take a blood thinning (anticoagulant) or steroid drug.Take other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others).Have 3 or more alcoholic drinks every day while using this product
Ingredients
In Each Caplet: Active Ingredients: Acetaminophen (250 mg), Pain Reliever; *Aspirin NSAID (250 mg), Pain Reliever; Caffeine (65 mg), Pain Reliever Aid. Inactive Ingredients: Benzoic Acid, Carnauba Wax, FD&C Blue No. 1, Hypromellose, Light Mineral Oil, Low-Substituted Hydroxypropyl Cellulose, Microcrystalline Cellulose, Polysorbate 20, Povidone, Propylene Glycol, Simethicone, Sorbitan Monolaurate, Stearic Acid, Titanium Dioxide. *Nonsteroidal Anti-inflammatory Drug.
Legal Disclaimer
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers find this migraine medication effective, with many reporting relief within an hour of taking it. The product receives positive feedback for its reliability, with one customer noting it lasts all day. Customers also appreciate its quick action and consider it good value for money.
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Customers find this medication highly effective for migraines, with many reporting it provides relief within an hour and consider it the best over-the-counter option for headaches.
"Works for me as advertised" Read more
"...a terrible migraine & let me tell you this right here is awesome, works great, I recommend. Fast delivery, value for money." Read more
"Works great and the price was great." Read more
"...In the past, these medications relieved my migraine in under an hour and I experienced little to no side effects...." Read more
Customers find the medication dependable and outstanding, with one customer noting that it lasts all day.
"good product" Read more
"Reliable product" Read more
"Dependable product!" Read more
"...Excedrin helps me within 30 minutes and lasts all day. I usually only need 1 tablet." Read more
Customers find the medication to be a good value for the money.
"Great value for the money" Read more
"...Fast delivery, value for money." Read more
"Works great and the price was great." Read more
"...that it's a hundred but it's only 25 pills for $4.68 so it's not worth the money" Read more
Customers find that the medication works quickly, with one customer noting it provides relief within 30 minutes.
"Works really fast" Read more
"I have used this product for years and absolutely love it. It works quickly and well." Read more
"My Absolute favorite Headache medication. Works super fast and completely helps my Headaches. Absolutely RECOMMEND 💯..." Read more
"...Excedrin helps me within 30 minutes and lasts all day. I usually only need 1 tablet." Read more
Reviews with images

Awesome
Top reviews from the United States
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- Reviewed in the United States on June 5, 2025It helps with the obstinate headaches
- Reviewed in the United States on June 6, 2025Works great on migraines
- Reviewed in the United States on May 27, 2025Starts working with in 30mins
- Reviewed in the United States on May 11, 2025Works for me as advertised
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Reviewed in the United States on April 15, 2025yo sufro de migraña y lo único que me das la paz y la tranquilidad y sobretodo que me quita el dolor inmediatamente son estas pastillas éstas son mis mejores aliadas
- Reviewed in the United States on April 23, 2025As described
- Reviewed in the United States on April 10, 2024I used to use products that didn’t work as well as the Excedrin
- Reviewed in the United States on April 7, 2025good product
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